Heart Burn Site

: Normally, the lower esophageal sphincter (LES) acts as a seal. If this muscle becomes loose or relaxes inappropriately, acid can leak through.

The primary cause is gastroesophageal reflux (GER), where stomach contents regurgitate into the esophagus. HEART BURN

: A condition where symptoms persist despite a normal endoscopy and even when acid suppression therapy fails. It is often linked to esophageal hypersensitivity , where the nerves in the esophagus are overly sensitive to even physiological (normal) levels of acid. Distinguishing Heartburn from Heart Attacks Heartburn or heart attack: When to worry - Mayo Clinic : Normally, the lower esophageal sphincter (LES) acts

: Unlike the stomach, the esophagus lacks a protective lining against acid and pepsin. Chronic exposure damages the mucosa and submucosa, triggering pain through deep-seated sensory nerves. triggering pain through deep-seated sensory nerves.