Standard 3DS consoles are region-locked. A Japanese (JPN) game will not naturally run on North American (USA) or European (PAL) hardware without system modifications.
Luigi Mansion 2 (ルイージマンション2). Release Date (JPN): March 20, 2013. Luigi Mansion 2 3DS (JPN) CIA
Unlike the single-mansion setting of the original, this sequel utilizes five distinct mansions and a mission-based structure. Legacy & Re-releases Standard 3DS consoles are region-locked