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The protein misfolds and is trapped inside the endoplasmic reticulum (ER) .

Utilizing fluorescently tagged TS045 (e.g., VSVG-GFP) to visualize live-cell membrane dynamics . Archive Details

The ts045 mutant is a . Researchers use it to "synchronize" protein movement:

Measuring the rate and efficiency of protein transport between different cellular compartments .

The protein folds correctly and moves as a wave from the ER to the Golgi complex and then to the plasma membrane (PM) . Common Uses in Research Reports